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News items on 'Leukaemia'
Cancer protein 'can be disarmed'
(BBC 12/11/2009)
Scientists have found a way to disarm a protein thought to play a key role in leukaemia and other cancers. The breakthrough raises hopes of a new type of therapy that could treat cancer and other diseases. Previous attempts to neutralise the protein had failed, leading experts to conclude it was effectively "undruggable". The study, carried out by the US Dana-Farber Cancer Institute, features in the journal Nature.
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Scientists claim leukaemia treatment breakthrough
(The Scotsman 03/11/2009)
SCIENTISTS have discovered a new drug which they claim is able to kill leukaemia, it was revealed yesterday. Researchers maintain that the drug, called PBOX-15, can even destroy the cancerous cells in adult patients with a poor prognosis and who have shown resistance to other treatments. The groundbreaking study was carried out by academics at Trinity College Dublin (TCD), in partnership with University of Sienna, Italy. Professor Mark Lawler, of TCD's school of medicine, said it could be another three to five years before the drug is used as a life-saving treatment.
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Mother can pass on cancer in womb
(BBC 13/10/2009)
Scientists have proved that it is possible for a mother's cancer cells to be passed to her unborn child. There are very rare cases where a mother and child appear to share the same cancer, but in theory the child's immune system should block the cancer. However, an analysis by a British-led team of one such case shows the cells which caused leukaemia in the child could only have come from the mother. The study appears in Proceedings of the National Academy of Sciences.
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(The Scotsman 28/09/2009)
A BROKEN genetic "switch" has been discovered that can trigger leukaemia. Scientists believe the discovery, revealing a previously unknown messaging mechanism in cells, could lead to new treatments. Leukaemia is a cancer of the bone marrow and the immune system's white blood cells, which do not develop properly and begin to divide uncontrollably. The disease leaves the body less able to fight infections. Leukaemia affects more than 7,000 people in the UK each year and causes 4,350 deaths.
Cancer gene complexity revealed
(BBC 07/08/2009)
Scientists have shown just how mind-bogglingly complex are the genetics underpinning the development of cancer. For the second time a team from Washington University has decoded the complete DNA of a patient with a form of leukaemia. But the suite of key genetic mutations they found were completely different from those uncovered following analysis of their first patient last year. The study appears in the New England Journal of Medicine.
Fresh hope for leukaemia sufferer Karla Neckles' plea for donor
(Mirror 11/06/2009)
Thousands of Daily Mirror readers have responded to leukaemia sufferer Karla Neckles' desperate appeal for a bone marrow donor. The young mum of Lenny, three, and six-month-old Joshua was diagnosed with the disease in January and has just weeks to live unless a match is found. Because Karla, 21, is mixed-race there are fewer donors on the register and doctors had been unable to find a match.
Inspiration Charlie, 6, loses his fight with leukaemia
(The Scotsman 02/06/2009)
A SIX-YEAR-OLD boy who inspired scores of people to donate bone marrow has lost his battle with leukaemia. Charlie Pearson had a rare form of the illness, which only surfaces twice a year in the UK, and passed away last week. He fronted an Evening News campaign over Christmas to encourage more people to join the bone marrow register, with nearly 100 people subsequently putting their name to the list in the Lothians. Unfortunately, the transplant was not a success and he died on May 19.
Cancer research 'lost in quake'
(BBC 09/04/2009)
A Hampshire cancer charity fears it may have lost two years' worth of research work in Monday's earthquake in Italy. Leukaemia Busters, which is based in Southampton, has been developing pioneering drugs in a clinic in the quake-hit city of L'Aquila. Dr David Flavell, from the charity, said it was likely specially engineered leukaemia cells used to produce anti-bodies had been lost. He said some laboratory staff had been hurt but no-one seriously.
How infection may spark leukaemia
(BBC 01/04/2009)
Scientists have shown how common infections might trigger childhood leukaemia. They have identified a molecule, TGF, produced by the body in response to infection that stimulates development of the disease. It triggers multiplication of pre-cancerous stem cells at the expense of healthy counterparts.
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