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News items on 'Cystic Fibrosis'
(BBC 09/11/2009)
Joe Dexter describes his band, Orange, as "Green Day meets The Cure". He wrote his first single at just 13 and three years later the American-based band had their first recording deal. Now, still aged just 21, British-born Joe has released his third album and finished a tour. His achievements are remarkable by any musical standards, but are even more so when you learn that Joe, who is the lead singer, has the lung condition cystic fibrosis - as well as asthma and diabetes.
Gene find 'may curb lung mucus'
(BBC 15/09/2009)
A genetic breakthrough raises hope of easing suffering for people with chronic lung disease - and maybe those just fighting a common cold. The biological reason why the lungs of people with conditions such as asthma and cystic fibrosis often clog up with thick mucus has been unclear. But Cincinnati Children's Hospital researchers have identified the main genetic switch behind the build-up. The Journal of Clinical Investigation study raises hopes of new treatments.
(BBC 19/07/2009)
Dr Nigel Brooke's desire to join the medical profession was one shaped by his own illness. As a child the 34-year-old consultant spent weeks at a time each year being treated for his cystic fibrosis. "I saw doctors working long hours, but I saw how rewarding it was," he said. "I realised that with my interest in science that was probably the way I would like to go.
Gene modifies lung disease impact
(BBC 26/02/2009)
Researchers have discovered a gene that modifies the severity of lung disease in people with the lethal genetic condition cystic fibrosis. The US study, published by Nature, may aid development of new treatments. The researchers deleted the key gene in mice, and then exposed the animals to a bacterium which often causes lung infections in cystic fibrosis patients [early research].
Cystic fibrosis gene cure closer
(BBC 17/02/2009)
US researchers say they are a step closer to developing a gene therapy cure for cystic fibrosis (CF). In lab tests their altered virus effectively delivered a new gene to replace the faulty one that causes CF and completely rid the lung of disease. Previous attempts have been hampered by the immune system mopping up the virus before it delivered its cargo.
Pictured: The 'fun-loving and beautiful' sisters killed by the same disease within 20 months of each other
(Daily Mail 29/11/2008)
Many sisters are very close but Jodi and Lucinda Dunmore had more reason than most to feel a strong bond. Both were born with cystic fibrosis and helped each other get the most out of life despite the lung disease. But, sadly, it ultimately also united them in death when the sisters passed away less than two years apart.
Pigs to aid research into cystic fibrosis
(The Scotsman 26/09/2008)
SCIENTISTS have created pigs with cystic fibrosis to help in the search for treatments for the devastating inherited disease.The pigs are the first animals to mimic the symptoms of the condition, which affects more than 8,000 people in the UK.Scientists expect the pigs to open up new areas of understanding about the disease, and help develop new treatments.
Drug hope for cystic fibrosis
(BBC 09/09/2008)
CF produces thick, sticky mucus that clogs the lungs and the pancreas, leading to life-threatening chest infections and problems with digestion. Trials suggest a new drug, VX-770 might restore function to defective proteins which cause the disease.
Venomous clues in lung bug battle
(BBC 08/09/2008)
Bacterial colonies in the lungs of cystic fibrosis patients use chemicals found in snake venom to attack them, research shows. The researchers hope a drug can be found to target the poisons.
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